Virulence gene of antithyroid drug-induced agranulocytosis in Northern Han Chinese found
Recently, Dr. He Yayi from the Department of Endocrinology of the First Affiliated Hospital of XJTU published her research paper on the journal Scientific Reportsentitled "Association of HLA-B and HLADRB1polymorphisms with antithyroid drug-induced agranulocytosis in a Han population from northern China".
This study was the first to report the susceptibility of the Han population from northern China to the antithyroid drug (ATD)-induced agranulocytosis, and is considered to be of great value in revealing the genetic factors of ATD-induced agranulocytosis. The study also explains the mechanisms of ATD-induced agranulocytosis from a genetic perspective, providing a novel therapeutic idea for improving the accuracy of clinical treatment of hyperthyreosis and individualized treatment.
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